One Step Forward in the Challenging Arena of MLL-AF4 Leukemia

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• 作者：Nancy J. Zeleznik-Le¹ ; ^{nzelezn@luc.edu" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Cancer Cell
• 出版年：2016
• 出版时间：14 November 2016
• 年：2016
• 卷：30
• 期：5
• 页码：657-658
• 全文大小：173 K

文摘

MLL-AF4 leukemia is the predominant infant acute leukemia and has a poor prognosis. No current experimental models accurately reflect the human disease. Lin et al., in this issue of Cancer Cell, describe their model that recapitulates multiple key aspects of this aggressive disease, facilitating future mechanistic and preclinical studies.