Cerebral blood flow-based evidence for mechanisms of low- versus high-frequency transcutaneous electric acupoint stimulation analgesia: A perfusion fMRI study in humans
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- 作者：Y. Jianga ; b ; c ; &dagger ; ; J. Liud ; &dagger ; ; J. Liue ; J. Hana ; b ; c ; X. Wangd ; ; C. Cuia ; b ; c ; clcui@bjmu.edu.cn" class="auth_mail
- 关键词：ANOVA ; analysis of variance ; ASL ; arterial spin labeling ; BOLD ; blood oxygen-dependent level ; CBF ; cerebral blood flow ; DMN ; default mode network ; EA ; electroacupuncture ; fMRI ; functional magnetic resonance imaging ; FOV ; field of view ; MTEAS ; mock TEAS ; ROI ; region of interest ; TEAS ; transcutaneous electric acupoint stimulation ; VAS ; visual analog scale
- 刊名：Neuroscience
- 出版年：30 May 2014
- 年：2014
- 卷：268
- 期：Complete
- 页码：180-193
- 全文大小：2790 K
文摘
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Forty-six subjects were treated with 2-, 100-Hz TEAS or MTEAS.
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A combined ASL-fMRI scanning and pain threshold testing model was performed.
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TEAS-analgesia started at 20 min during the treatment, and MTEAS was not effective.
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CBF and regional CBF revealed a trend of early activation with later inhibition.
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Key regions related to 2- and 100-Hz TEAS-analgesia are distinct and overlapping.