Oxyresveratrol protected hepatocytes against oxidative stress, mitochondrial damage, and resultant cell death.
Oxyresveratrol also ameliorated acute liver injury caused by CCl<sub>4sub> in mice.
Oxyresveratrol induced activation of an antioxidant transcription factor, Nrf2, mediated through ERK phosphorylation.
These events may have a role in its protective effects in the liver.