MAOA-VNTR polymorphism modulates context-dependent dopamine release and aggressive behavior in males
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- 作者：Thorben Schlü ; tera ; tschlueter@ukaachen.de" class="auth_mail" title="E-mail the corresponding author ; Oliver Winzb ; Karsten Henkela ; Thomas Eggermannc ; Siamak Mohammadkhani-Shalib ; Claudia Dietricha ; Alexander Heinzelb ; g ; Michel Deckera ; Paul Cummingd ; e ; Klaus Zerresc ; Markus Pielf ; Felix M. Mottaghyb ; g ; h ; Ingo Vernalekena ; g
- 关键词：Dopamine ; PET ; DMFP ; Aggression ; MAOA
- 刊名：NeuroImage
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：125
- 期：Complete
- 页码：378-385
- 全文大小：375 K
文摘
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Two groups of the so-called “warrior” genotype, MAOA uVNTR polymorphism were selected.
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Dopamine release during violent movie content was analyzed vs. provoked aggression.
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The MAOA-groups showed inversed changes of aggression after violent movie perception.
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Dopamine release was also inversely regulated between genetic groups.
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No support for simple dopaminergic pathways of aggression driven by MAOA-activity.