The pathophysiological mechanisms of diabetic otopathy

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• 作者：Mohammed Al-Hariri ; Ph.D ; ^{mohd_alhariri@yahoo.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Auditory ; Diabetes mellitus ; Diabetic otopathy ; Molecular mechanisms ; Vestibular
• 刊名：Journal of Taibah University Medical Sciences
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：11
• 期：4
• 页码：401-403
• 全文大小：478 K

文摘

Nearly all systems in the body are affected by the metabolic disarrangement of diabetes mellitus. Consequently, a serious signaling pathway may develop that can potentially lead to several adverse complications. Diabetic otopathy (DO) is a clinical syndrome characterized by hearing impairment due to the toxic effect of diabetes mellitus. Evidence-based studies have indicated a significant relationship between vestibular and/or auditory disorders and diabetes mellitus. A screening test for DO has been suggested in all diabetic patients with long-standing disease. Further clinical trials are warranted to explore the molecular mechanisms of DO.