Synthesis of α-santonin derived acetyl santonous acid triazole derivatives and their bioevaluation for T and B-cell proliferation
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- 作者：Nisar A. Dangrooa ; Jasvinder Singhb ; c ; 1 ; Alamgir A. Dara ; 1 ; Nidhi Guptaa ; Praveen K. Chinthakindia ; Anpurna Kaulb ; c ; Mohmmed A. Khurood ; Payare L. Sangwana ; c ; plsangwan@iiim.ac.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：α-Santonin ; Santonous acid triazole ; Immunosuppresants ; ConA ; LPS ; T and B cell
- 刊名：European Journal of Medicinal Chemistry
- 出版年：2016
- 出版时间：14 September 2016
- 年：2016
- 卷：120
- 期：Complete
- 页码：160-169
- 全文大小：613 K
文摘
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Synthesis of 30 α-santonin derivatives.
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Several derivatives were found immunosuppressive agents.
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The molecules showed diminutive effect on ConA T-cell and LPS-induced B-cell proliferation.