DNA-Targeted Precision Medicine; Have We Been Caught Sleeping?

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• 作者：William C. Reinhold¹ ; ^{wcr@mail.nih.gov} ; Anish Thomas¹ ; ² ; Yves Pommier¹
• 关键词：DNA-damaging agents ; precision medicine
• 刊名：Trends in Cancer
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：3
• 期：1
• 页码：2-6
• 全文大小：1204 K
• 卷排序：3

文摘

In the current drive to incorporate molecular markers into treatment selection for precision medicine, there has been a significant and, we believe, ill-advised omission of the large and routinely used group of drugs whose mechanism of action is DNA damage.