Africa green monkey cell lines were monitored for human adenovirus 11p GFP vector infection.

Human CD46 molecules were detectable in these monkey cell lines.

Adenovirus 11p GFP vector can be propagated in Vero cells increases the safety of Ad11p-based vectors for clinical trials.

To use Vero cells for preparation of Ad11p vector avoids the potential inclusion of oncogenes from tumor cells.