PEGylation of platinum bio-electrodes

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• 作者：Zhilian Yue ; Paul J. Molino ; Xiao Liu ; Gordon G. Wallace ; ^{gwallace@uow.edu.au}
• 关键词：PEGylation ; Protein adsorption ; Quartz crystal microbalance-dissipation ; Platinum electrode ; Neural prosthesis ; Cochlear implants
• 刊名：Electrochemistry Communications
• 出版年：2013
• 出版时间：February, 2013
• 年：2013
• 卷：27
• 期：Complete
• 页码：54-58
• 全文大小：608 K

文摘

Controlling protein interactions at the implanted electrode interface is becoming an important strategy for the management of foreign body responses that have proven to be detrimental to the long-term performance of neural prosthesis. In this study, PEGylation was conducted on platinum bio-electrodes to render the surface protein-resistant. The PEGylated electrode was investigated using a quartz crystal microbalance-dissipation, electrochemical impedance spectroscopy and cyclic voltammetry.