Vertex-wise examination of depressive symptom dimensions and brain volumes in older adults

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• 作者：Molly E. McLaren^a ; Sarah M. Szymkowicz^a ; Andrew O'Shea^a ; ^b ; Adam J. Woods^a ; ^b ; ^c ; Stephen D. Anton^d ; Vonetta M. Dotson^a ; ^b ; ^c ; ^{vonetta@phhp.ufl.edu}
• 关键词：Depressive symptoms ; Symptom dimensions ; Aging ; Brain ; MRI ; Vertex-wise analysis
• 刊名：Psychiatry Research: Neuroimaging
• 出版年：2017
• 出版时间：28 February 2017
• 年：2017
• 卷：260
• 期：Complete
• 页码：70-75
• 全文大小：325 K
• 卷排序：260

文摘

Relationships between depressive symptom dimensions and brain volumes were examined. Distinct associations between volumes and different symptom dimensions were found. Depressive symptoms had both positive and negative associations with volumes. Results highlight the importance of separately examining depressive symptom clusters.