Isolation, expression analysis and characterization of NEFA-interacting nuclear protein 30 and RING finger and SPRY domain containing 1 in skeletal muscle
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- 作者：David S. Waddell ; d.s.waddell@unf.edu" class="auth_mail" title="E-mail the corresponding author ; Paige J. Duffin1 ; Ashley N. Haddock1 ; Virginia E. Triplett ; Jason J. Saredy ; Karina M. Kakareka ; John T. Eldredge
- 关键词：BioGRID ; Biological General Repository for Interaction Datasets ; bp ; base pair ; bHLH ; basic helix-loop-helix ; CDD ; Conserved Domain Database ; DMEM ; Dulbecco's Modified Eagle Medium ; FBS ; Fetal Bovine Serum ; Fam192a ; family with sequence similarity 192 ; member a ; GEO ; Gene Expression Omnibus ; GFP ; Green Fluorescent Protein ; MAFbx ; Muscle Atrophy F-box ; M-MLV ; Moloney Murine Leukemia Virus ; MuRF1 ; Muscle RING Finger 1 ; MyHC ; myosin heavy chain ; NCBI ; National Center for Biotechnology Information
- 刊名：Gene
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：576
- 期：1
- 页码：319-332
- 全文大小：2838 K
文摘
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Nip30/Fam192a and Rspry1 are expressed in skeletal muscle.
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Nip30/Fam192a and Rspry1 share a common 230 base pair regulatory region.
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The Nip30-Rspry1 common promoter region contains a conserved E-box element.
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MyoD1 induces Nip30 and Rspry1 reporter activity in an E-box-dependent manner.
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Nip30 localizes to the nucleus and Rspry1 localizes to the cytoplasm in cells.