Left ventricular twist in clinically stable heart transplantation recipients: A speckle tracking echocardiography study

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• 作者：Matteo Cameli ; Piercarlo Ballo ; Matteo Lisi ; Susanna Benincasa ; Marta Focardi ; Sonia Bernazzali ; Gianfranco Lisi ; Massimo Maccherini ; Michael Henein ; Sergio Mondillo
• 关键词：LV function ; Torsion ; Heart transplantation ; Echocardiography ; Speckle tracking
• 刊名：International Journal of Cardiology
• 出版年：2013
• 出版时间：20 September, 2013
• 年：2013
• 卷：168
• 期：1
• 页码：357-361
• 全文大小：443 K

文摘

Background and aim

Cavity twist is an integral part of LV function and its pattern in transplanted hearts is not well known. This study aimed at exploring LV twist in clinically stable heart transplant (HT) recipients with no evidence for rejection.

Methods

We studied 32 HT patients (54 ¡À 24 months after HT), 34 other cardiac surgery (CS) patients and compared them with 35 health controls using speckle tracking echocardiography, measuring peak twist angle, time-to-peak twist, and untwist rate.

Results

LV twist angle was smaller in the HT group (6.2 ¡À 3.3¡ã) in comparison with the CS group and controls (13.2 ¡À 3.5¡ã and 13.1 ¡À 4.5¡ã, respectively; p < 0.0001 for all) and untwist rate was reduced (HT group: ? 74 ¡À 30¡ã/s; CS group: ? 118 ¡À 43¡ã/s; controls: ? 116 ¡À 39¡ã/s; p < 0.0001 for all). Time-to-peak twist was not different between groups. Time after HT was the main independent predictor of both LV twist angle and untwist rate (¦Â = 0.8, p < 0.0001).

Conclusion

Though clinically stable, LV twist dynamics are significantly impaired in HT recipients, even in comparison with patients who underwent other cardiac surgery.