A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage

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• 作者：Taylor Eddens^a ; Eunkyung Song^b ; Monica I. Ardura^b ; Jay K. Kolls^a ;
• 关键词：Pneumocystis ; GMS diagnosis ; Antimicrobial resistance ; Life cycle
• 刊名：Medical Mycology Case Reports
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：11
• 期：Complete
• 页码：48-52
• 全文大小：707 K

文摘

We report a case of Pneumocystis pneumonia in a 5-year-old male with Trisomy 21 and acute lymphoblastic leukemia. The lack of response to trimethoprim-sulfamethoxazole raised concerns for antimicrobial resistance. Further, diagnosis of Pneumocystis in this patient was complicated by a GMS-negative bronchoalveolar lavage despite molecular evidence of Pneumocystis infection.