Synthetic strategies to prepare 2-alkyl, 2-aryl and 2-acetylenyl substituted 4,6-diamino-1,3,5-triazines
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- 作者：Christian A.G.N. Montalbetti ; Thomas S. Coulter ; Muhammed K. Uddin ; Serge G. Reignier ; Filippo Magaraci ; Charlotta Grå ; nä ; s ; Christian Krog-Jensen and Jakob Felding
- 关键词：Triazine ; Sonogashira ; Suzuki ; Nucleophilic substitution ; PI3 Kinase pathway inhibitors ; FOXO1 Translocation
- 刊名：Tetrahedron Letters
- 出版年：2006
- 出版时间：14 August 2006
- 年：2006
- 卷：47
- 期：33
- 页码：5973-5975
- 全文大小：89 K
文摘
We have developed synthetic protocols to generate 2-alkyl, 2-aryl and 2-acetylenyl substituted 4,6-diamino-1,3,5-triazines from the corresponding 2-chloro compound.