Unification of [FeFe]-hydrogenases into three structural and functional groups
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- 作者：Saroj Poudela ; saroz189@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Monika Tokmina-Lukaszewskab ; tokminalukas@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Daniel R. Colmana ; daniel.colman@montana.edu" class="auth_mail" title="E-mail the corresponding author ; Mohammed Refaib ; refai1982@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Gerrit J. Schutc ; gerti@uga.edu" class="auth_mail" title="E-mail the corresponding author ; Paul W. Kingd ; Paul.King@nrel.gov" class="auth_mail" title="E-mail the corresponding author ; Pin-Ching Manessd ; PinChing.Maness@nrel.gov" class="auth_mail" title="E-mail the corresponding author ; Michael W.W. Adamsc ; adams@bmb.uga.edu" class="auth_mail" title="E-mail the corresponding author ; John W. Petersb ; john.peters@chemistry.montana.edu" class="auth_mail" title="E-mail the corresponding author ; Brian Bothnerb ; bbothner@montana.edu" class="auth_mail" title="E-mail the corresponding author ; Eric S. Boyda ; eboyd@montana.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：[FeFe]-hydrogenase ; Hydrogen ; Electron bifurcation ; Post-translational modification ; Regulation ; Bioinformatics
- 刊名：Biochimica et Biophysica Acta (BBA) - General Subjects
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：1860
- 期：9
- 页码：1910-1921
- 全文大小：1603 K
文摘
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Three primary classes/groups of [FeFe]-hydrogenases (Hyd) were identified.
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Variation in F-, C- and H-cluster domains of Hyd did not vary by group classification.
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Hyd that bifurcate are multimeric and belong to two of the three classes.
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Regulatory proteins encoded in multimeric Hyd gene neighborhoods were identified.
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Mass spectrometry of multimeric Hyd indicates post-translational modification.