On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments
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- 作者：Marco Pirazzinia ; Domenico Azarnia Tehrana ; Oneda Lekaa ; Giulia Zanettia ; Ornella Rossettoa ; Cesare Montecuccoa ; b ; cesare.montecucco@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Botulinum neurotoxin isoforms ; Clostridia ; Duration of neuroparalysis ; Endocytosis ; Presynaptic binding ; Translocation
- 刊名：Biochimica et Biophysica Acta (BBA)-Biomembranes
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：1858
- 期：3
- 页码：467-474
- 全文大小：1162 K
文摘
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Provides a comprehensive review of membrane translocation of botulinum neurotoxins
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Presents a parallel analysis of possible models for the membrane translocation
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Discusses a novel model
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Suggests novel experiments to test current models