Association between high expression macrophage migration inhibitory factor (MIF) alleles and West Nile virus encephalitis
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- 作者：Rituparna Dasa ; b ; Kerry Loughrana ; Charles Murchisona ; Feng Qiana ; 1 ; Lin Lenga ; Yan Songa ; Ruth R. Montgomerya ; ruth.montgomery@yale.edu" class="auth_mail" title="E-mail the corresponding author ; Mark Loebc ; Richard Bucalaa
- 关键词：West Nile virus ; Mosquito vector ; Immune response ; Macrophage ; Neurologic disease
- 刊名：Cytokine
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：78
- 期：Complete
- 页码：51-54
- 全文大小：346 K
文摘
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West Nile virus infection is usually asymptomatic but may cause severe encephalitis.
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The cytokine macrophage migration inhibitory factor is elevated in WNV encephalitis.
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Patients with high-expression MIF alleles are more likely to have WNV encephalitis.
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MIF genotype in WNV patients may be useful for prognostic or therapeutic targets.