Kalkipyrone B, a marine cyanobacterial γ-pyrone possessing cytotoxic and anti-fungal activities
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- 作者：Matthew J. Bertina ; Ozlem Demirkiranb ; Gabriel Navarroa ; Nathan A. Mossa ; John Leea ; c ; Gregory M. Goldgofd ; Edgar Vigild ; Elizabeth A. Winzelerd ; Fred A. Valeriotee ; William H. Gerwicka ; f ; wgerwick@ucsd.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cyanobacteria ; Polyketide ; Kalkipyrone ; Yoshinone ; Leptolyngbya ; Moorea ; Schizothrix
- 刊名：Phytochemistry
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：122
- 期：Complete
- 页码：113-118
- 全文大小：833 K
文摘
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Bioassay guided isolation gave three γ-pyrones from a marine cyanobacterium.
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Kalkipyrone B was determined by NMR and Mosher’s ester analysis.
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Kalkipyrone A was cytotoxic while kalkipyrone A and B were equipotent antifungals.
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16S rRNA analysis identified the producing strain to be a Leptolyngbya species.