Ecotoxicological risk assessment of the “Acid Black 210” dye

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• 作者：Otá ; vio Pelegrino Rocha^a ; ^{otavio@fcfrp.usp.br} ; ^{otavio_pelegrino@yahoo.com.br} ; Cibele Aparecida Cesila^a ; Elisa Maria Christovam^b ; Sí ; lvia Berlanga de Moraes Barros^c ; Maria Valnice Boldrin Zanoni^b ; Danielle Palma de Oliveira^a ; ^{dpalma@usp.br}
• 关键词：Acid Black 210 ; Dye ; Ecotoxicological risk assessment
• 刊名：Toxicology
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：376
• 期：Complete
• 页码：113-119
• 全文大小：740 K
• 卷排序：376

文摘

The “Acid Black 210” dye is one of the most used black dyes by the leather industry. This compound contains three azo groups in its chemical structure, and has been quoted as a non-regulated dye with toxicological concern, since it could generate carcinogenic aromatic amines. The objective of this study was to perform the ecotoxicological risk assessment of this dye through testing its toxicity in vitro and in vivo with the Ames test, the Comet assay, the Daphnia similis test, and the zebrafish embryo acute toxicity test. Moreover, we evaluated the presence of this dye in environmental samples related with a tannery industry. All the tests performed were negative, with the exception of the Ames test with the Salmonella typhimurium TA98 strain, which resulted in a low mutagenic potency. Due to the low concentrations of the “Acid Black 210” dye found in tannery effluents, and the high concentrations where any toxic activity is occasionally described, we concluded that this dye is safe from the ecotoxicological point of view in the areas evaluated and in the light of the current knowledge.