Exploiting the biological roles of the trypsin inhibitor from Inga vera seeds: A multifunctional Kunitz inhibitor
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- 作者：Cé ; zar da Silva Bezerraa ; b ; c ; Caio Fernando Ramalho de Oliveirac ; Olga Lima Tavares Machadod ; Gabriela Souto Vieira de Melloe ; Maira Galdino da Rocha Pittae ; Moacyr Jesus Barreto de Melo Rê ; goe ; Thiago Henrique Napoleã ; of ; Patrí ; cia Maria Guedes Paivaf ; Suzanna de Fá ; tima Ferreira Ribeirog ; Valdirene Moreira Gomesg ; Osmar Nascimento Silvah ; Simone Maria-Netoc ; Octá ; vio Luiz Francoh ; Maria Lí ; gia Rodrigues Macedoa ; b ; c ; bioplant@terra.com.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Inga vera ; Plant-defense ; Kunitz inhibitor ; Antimicrobial ; Anticancer ; Bioinsecticidal
- 刊名：Process Biochemistry
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：51
- 期：6
- 页码：792-803
- 全文大小：2905 K
文摘
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Inga vera trypsin inhibitor (IVTI) is a Kunitz-type inhibitor composed of a single 20 kDa polypeptide chain.
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IVTI inhibits the trypsin-like enzymes from several lepidopteran pests.
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IVTI impairs the weight gain, survival and larval cycle of Anagasta kuehniella.
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IVTI is a fungicidal to Candida buinensis.
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IVTI prevents the proliferation of colorectal adenocarcinoma cells (CACO-2).