In situ production of ROS in the skin by photodynamic therapy as a powerful tool in clinical dermatology
详细信息 查看全文
- 作者：Pablo Fonda-Pascuala ; b ; 1 ; Oscar M. Moreno-Arronesa ; b ; 1 ; Adrian Alegre-Sancheza ; b ; 1 ; David Saceda-Corraloa ; b ; 1 ; Diego Buendia-Castañ ; oa ; Cristina Pindado-Ortegaa ; Pablo Fernandez-Gonzaleza ; Kyra Velazquez-Kennedyb ; Marí ; a I. Calvo-Sá ; nchezb ; Antonio Harto-Castañ ; oa ; Bibiana Perez-Garciaa ; Lorea Bagazgoitiaa ; b ; Sergio Vañ ; o-Galvana ; b ; Jesus Espadac ; jespada@iib.uam.es" class="auth_mail" title="E-mail the corresponding author ; Pedro Jaen-Olasoloa ; pedro@pjaen.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Dermatology ; Reactive oxygen species ; Protoporphyrin-IX ; Clinical indications ; Photorejuvenation ; Tissue regeneration
- 刊名：Methods
- 出版年：2016
- 出版时间：15 October 2016
- 年：2016
- 卷：109
- 期：Complete
- 页码：190-202
- 全文大小：3356 K
文摘
- •
PDT is based on a PpIX-dependent generation of ROS in the tissue.
- •
Current indications for PDT in dermatology involve direct killing of cell targets.
- •
225">However, new dermatoses regarding tissue regeneration and aging are being assayed.
- •
These observations suggest that ROS can have physiological roles in human skin.