Effects of IFNγ administration on allograft rejection in ginbuna crucian carp
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- 作者：Yasuhiro Shibasaki ; Chihiro Hatanaka ; Yuta Matsuura ; Ryuichiro Miyazawa ; Takeshi Yabu ; Tadaaki Moritomo ; Teruyuki Nakanishi ; nakanishi.teruyuki@nihon-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Allograft rejection ; Cell-mediated immunity ; Ginbuna crucian carp ; Interferon gamma ; Interferon gamma related
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：62
- 期：Complete
- 页码：108-115
- 全文大小：1127 K
文摘
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Expression of IFNγrel 1 mRNA significantly increased during acute allograft rejection.
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Recombinant IFNγrel 1 administration increased T cells and sIgM+ cells in scale allografts and enhanced allograft rejection.
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Expression of IFNγ1, IFNγ2 and effector molecule mRNA was up-regulated by rgIFNγrel 1 administration.