Stress during the gestational period modifies pups’ emotionality parameters and favors preference for morphine in adolescent rats
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- 作者：Luciana Taschetto Veya ; Higor Zuquetto Rosac ; Raquel Cristine Silva Barcelosb ; Hecson Jesser Segata ; Viní ; cia Garzella Metzc ; Verô ; nica Tironi Diasb ; Thiago Duarteb ; Marta M.M.F. Duarteb ; d ; Marilise Escobar Burgera ; b ; c ; mariliseeb@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Addiction ; Anxiety ; Gestational stress ; Post-natal stress ; Morphine
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：296
- 期：Complete
- 页码：408-417
- 全文大小：1632 K
文摘
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Pups exposed to gestational stress (Gest-S) showed smaller body weight gain.
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Gest-S increased and post-NS decreased pups’ corticosterone plasma levels.
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Gest-S-exposed rats showed increased emotionality and stress-related behaviors.
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Gest-S exposure increased morphine-conditioned place preference.
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Endogenous opiate system may be changed by Gest-S, altering responses to opiate drugs.