The Slav-cleft: A three-center study of the outcome of treatment of cleft lip and palate. Part 1: Craniofacial morphology

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• 作者：Wanda Urbanova^a ; Irena Klimova^b ; Andrzej Brudnicki^c ; Petra Polackova^a ; Daniela Kroupova^b ; Ivana Dubovska^d ; Martin Rachwalski^e ; Piotr Stanislaw Fudalej^d ; ^f ; ^{piotr.fudalej@zmk.unibe.ch" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Cleft lip ; Cleft palate ; Cephalometrics ; Geometric morphometrics ; Morphology ; Slavs
• 刊名：Journal of Cranio-Maxillofacial Surgery
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：44
• 期：11
• 页码：1767-1776
• 全文大小：1732 K

文摘

Results of a comparison of the outcomes of treatment of cleft lip and palate can be affected by growth characteristics of populations from which subjects with the clefts are derived. Moreover, conventional cephalometric techniques used in cleft studies for analysis of facial morphology provide only a partial description of shape and are confounded by biases regarding the reference structures. In this retrospective comparison, craniofacial morphology of preadolescent patients with unilateral cleft lip and palate treated in Warsaw (n = 35, age = 10.6 years, SD = 1.2), Prague (n = 38, age = 11.6 years, SD = 1.4), and Bratislava (n = 26, age = 10.5 years, SD = 1.6) were evaluated on cephalograms with the cephalometric method used in the Eurocleft study and geometric morphometrics. We found that patients treated in Warsaw showed slightly more favorable outcomes than in Prague and Bratislava. The differences were related primarily to the position of maxillary alveolar process, cranial base, mandibular angle, and soft tissues. Although no association between a component of treatment protocol and the outcome was found, it is possible that organizational factors such as participation of high-volume, experienced surgeons contributed to these results.