Ultrasound-targeted microbubble destruction: toward a new strategy for diabetes treatment
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- 作者：Masoud Mozafari1 ; mozafari.masoud@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Masayuki Shimoda2 ; Aleksandra M. Urbanska3 ; Sophie Laurent4
- 刊名：Drug Discovery Today
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：21
- 期：4
- 页码：540-543
- 全文大小：655 K
文摘
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UTMD offers a unique mechanism for gene delivery owing to the use of lipid-shelled microbubbles.
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UTMD allows the genes to transfer into the inefficient pancreas without viral vector utilization.
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UTMD enables not only islet regeneration but also normalization of blood sugar, insulin and C-peptide.