Inhibition by ketamine and amphetamine analogs of the neurogenic nitrergic vasodilations in porcine basilar arteries
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- 作者：Mei-Fang Chena ; b ; g ; Su-Yu Laid ; Po-Cheng Kungd ; Yo-Cheng Lind ; Hui-I Yanga ; Po-Yi Chena ; d ; Ingrid Y. Liue ; Ahai Chang Luaf ; Tony Jer-Fu Leea ; b ; c ; d ; h ; tlee@mail.tcu.edu.tw" class="auth_mail" title="E-mail the corresponding author ; tlee@siumed.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Methamphetamine ; Amphetamine ; Ketamine ; Nicotinic acetylcholine receptor ; Basilar artery ; Nitrergic neurogenic vasodilation ; Sympathetic-parasympathetic interaction
- 刊名：Toxicology and Applied Pharmacology
- 出版年：2016
- 出版时间：15 August 2016
- 年：2016
- 卷：305
- 期：Complete
- 页码：75-82
- 全文大小：921 K
文摘
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Ketamine/amphetamines inhibit nicotine-induced cerebral neurogenic vasdilation.
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Ketamine/amphetamines block cerebral perivascular sympathetic nAChR-mediated current.
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The inhibitory potency is ketamine > d-amphetamine > methamphetamine > OH-amphetamine.