Effects of repeated high-dose methamphetamine and ceftriaxone post-treatments on tissue content of dopamine and serotonin as well as glutamate and glutamine
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- 作者：Yusuf S. Althobaitia ; Atiah H. Almalkia ; b ; Sujan C. Dasa ; b ; Fahad S. Alshehria ; Youssef Saria ; b ; youssef.sari@utoledo.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Methamphetamine ; Dopamine ; Serotonin ; Glutamate ; Glutamine ; Ceftriaxone
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：10 November 2016
- 年：2016
- 卷：634
- 期：Complete
- 页码：25-31
- 全文大小：979 K
文摘
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Methamphetamine caused depletion of dopamine and 5-HT in NAc and PFC.
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Dopamine tissue content was restored with ceftriaxone post-treatment in NAc.
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Methamphetamine decreased glutamate and glutamine tissue content in PFC.
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Ceftriaxone attenuated the effect of methamphetamine on glutamate and glutamine.