Dmrt1 is necessary for male sexual development in zebrafish
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- 作者：Kaitlyn A. Webster<sup>asup> ; Ursula Schach<sup>bsup> ; Angel Ordaz<sup>csup> ; Jocelyn S. Steinfeld<sup>asup> ; Bruce W. Draper<sup>csup> ; Kellee R. Siegfried<sup>asup><sup> ; sup><sup>kellee.siegfried@umb.edusup>
- 关键词：Zebrafish ; Sex-determination ; Testis ; Gonad ; Spermatogenesis ; Dmrt1
- 刊名：Developmental Biology
- 出版年：2017
- 出版时间：1 February 2017
- 年：2017
- 卷：422
- 期：1
- 页码：33-46
- 全文大小：2081 K
- 卷排序：422
文摘
Zebrafish dmrt1 mutants primarily develop as fertile females. Rare dmrt1 mutant males have aberrant testis development and are sterile. Dmrt1 counteracts ovary-promoting signals from the germ line. Dmrt1 has an early role in gonadal sex differentiation in male zebrafish.