Five-fold increased risk of relapse following breaks in antipsychotic treatment of first episode psychosis

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• 作者：Toby T Winton-Brown ; MRCPsych PhD¹ ; Thomas Elanjithara ; MRCPsych¹ ; Paddy Power ; FRCPsych MD ; Ricardo Coentre ; MD ; Pablo Blanco-Polaina ; MD ; Philip McGuire ; FRCPsych PhD ; ^{Philip.McGuire@kcl.ac.uk}
• 刊名：Schizophrenia Research
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：179
• 期：Complete
• 页码：50-56
• 全文大小：396 K
• 卷排序：179

文摘

Non adherence with anti-psychotic medication once positive symptoms have improved in first episode psychosis is common; clinicians may trial a break in treatment However in this 18 month follow-up study when medication was interrupted remission took longer and relapses were five times commoner Clinicians should carefully consider the cost of relapse when advising patients and carers on the length of treatment following first episode psychosis