mRNA levels of seven genes involved in DNA repair pathways were evaluated.
The examined genes had tendency to be down-regulated in the cells treated with EMF.
GADD45A mRNA levels in cells co-treated with cisplatin (CDDP) + EMF were increased.
Co-treatment of CDDP + EMF enhances down-regulation of the genes of NHEJ pathway.
Elevation in IC50 of CDDP when cells co-treated with CDDP + EMF was observed.