Involvement of mast cells and histamine in edema induced in mice by Scolopendra viridicornis centipede venom
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- 作者：Bianca C.L.F. Tá ; voraa ; Louise F. Kimuraa ; Marta M. Antoniazzib ; Thiago M. Chiarielloc ; Eliana L. Faquim-Mauroa ; Katia C. Barbaroa ; katia.barbaro@butantan.gov.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Centipede venom ; Scolopendra ; Inflammation ; Mast cell and histamine
- 刊名：Toxicon
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：121
- 期：Complete
- 页码：51-60
- 全文大小：2290 K
文摘
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Mast cells and histamine are involved in the inflammatory cascade developed by Scolopendra viridicornis venom.
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The role of histamine in edema formation induced by Scolopendra viridicornis venom is mainly via the H1 receptor.
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Scolopendra viridicornis venom has a direct effect on mast cells lines in vitro.
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Scolopendra viridicornis venom promotes cytokines, chemokine and eicosanoid production by mast cell lines in vitro.