A new runaway criterion to distinguish different reactor behaviors (IS, MI, TR and QFS) is proposed.
The chemical process may be in a potential runaway situation if θMTSR < 1.
A robust procedure to identify generalized inherently safe (GIS) operating conditions for isoperibolic homogeneous SBRs is proposed with limited kinetic information.
The determined GIS operating conditions involve the information of both a sufficiently low accumulation and MTSR lower than MAT.