Factors associated with syphilis seroreactivity among polydrug users in Northeast Brazil: A cross-sectional study using Respondent Driven Sampling

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• 作者：Cremildo Joã ; o Baptista^a ; ^{cjbpatista.moz@gmail.com} ; Ines Dourado^b ; Sandra Brignol^c ; Tarcí ; sio de Matos Andrade^d ; Francisco Iná ; cio Bastos^e
• 关键词：Drug use ; Sexual behaviour ; Syphilis seroreactivity ; Risk factors ; Hard-to-reach populations ; Brazil
• 刊名：International Journal of Drug Policy
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：39
• 期：Complete
• 页码：37-42
• 全文大小：327 K
• 卷排序：39

文摘

The burden of sexually transmitted infections (STIs), such as syphilis, is higher in low-income countries, with serious consequences and profound impact on sexual and reproductive health and human immunodeficiency virus (HIV) spread. Syphilis prevalence tend to be higher among people who misuse drugs than in the general population.ObjectiveTo assess syphilis and associated factors among polydrug users (PDU) in the city of Salvador, Northeast Brazil.MethodsA cross-sectional study was conducted in 10 Brazilian cities between September and November 2009 using Respondent Driven Sampling (RDS). Participants answered an Audio Computer-Assisted Self Interview (ACASI) and were rapid tested for HIV and syphilis. We performed multivariable regression models for correlates of syphilis on Stata 10.0. Estimates were weighted by the inverse size of the individual social network size and homophily.ResultsMean age was 29.3 years (range: 18–62), 74.0% were males, and 89.8% were non-white. Syphilis prevalence was 16.6%. Females (adjwOR:2.14; 95%CI:1.09–4.20), individuals over 29 years old (adjwOR:4.44; 95%CI:2.41–8.19), those who exchanged sex for money or drugs (adjwOR:3.51; 95%CI:1.84–6.71), “No/low” self-perceived risk of HIV infection (adjwOR:5.13; 95%CI:1.36–19.37), and having nine or less years of education (adjwOR:2.92; 95%CI:1.08–7.88) were associated with syphilis.ConclusionOne of the most pressing needs for syphilis prevention/control is the availability of rapid point-of-care diagnostic tests and treatment. Interventions should be tailored to PDU needs and their multiple burdens as shown in the present study, that may contribute to future studies aiming to better understand the relationships between drug use and syphilis.