Solid-state NMR spectroscopy in pharmaceutical research and analysis
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- 作者：Robert T. Berendt ; Diana M. Sperger ; Eric J. Munson and Paul K. Isbester
- 关键词：Dosage form ; Excipient ; Pharmaceutical analysis ; Polymorph ; Solid-state NMR spectroscopy
- 刊名：TrAC Trends in Analytical Chemistry
- 出版年：2006
- 出版时间：November 2006
- 年：2006
- 卷：25
- 期：10
- 页码：977-984
- 全文大小：200 K
文摘
In this review, we discuss the motivation for using solid-state NMR (SSNMR) spectroscopy to study pharmaceutical solids, and then give an overview of the information obtained through SSNMR experiments. In addition, we explain the basics of SSNMR spectroscopy and describe several applications to the pharmaceutical field.