Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle
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- 作者：Robert S. Lee-Young1 ; robert.lee-young@monash.edu" class="auth_mail" title="E-mail the corresponding author ; Nolan J. Hoffman4 ; 9 ; Kate T. Murphy5 ; Darren C. Henstridge1 ; Dorit Samocha-Bonet4 ; Andrew L. Siebel3 ; 10 ; Peter Iliades1 ; Borivoj Zivanovic1 ; Yet H. Hong6 ; Timothy D. Colgan2 ; Michael J. Kraakman1 ; Clinton R. Bruce7 ; Paul Gregorevic2 ; Glenn K. McConell6 ; Gordon S. Lynch5 ; Grant R. Drummond8 ; Bronwyn A. Kingwell3 ; Jerry R. Greenfield4 ; Mark A. Febbraio1 ; 4 ; m.febbraio@garvan.org.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：Glucose metabolism ; Enzyme activity ; Insulin sensitivity
- 刊名：Molecular Metabolism
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：5
- 期：11
- 页码：1083-1091
- 全文大小：1063 K
文摘
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Defective skeletal muscle G6PDH activity in multiple insulin resistant animal models.
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Demonstration of defective skeletal muscle G6PDH activity in pre-diabetic individuals.
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Identification of nNOSμ as a regulator of G6PDH activity in skeletal muscle.
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G6PDH activity modulates insulin-independent glucose uptake in skeletal muscle.