Comparison of the performance of two mycobacteriophage D29-based protocols for fluoroquinolone susceptibility testing in Mycobacterium tuberculosis
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- 作者：Emma J. Stella ; Agustina I. de la Iglesia ; Hé ; ctor R. Morbidoni
- 关键词：Drug susceptibility testing ; Fluoroquinolones ; Mycobacteriophages ; Mycobacterium tuberculosis
- 刊名：Journal of Microbiological Methods
- 出版年：2009
- 出版时间：December 2009
- 年：2009
- 卷：79
- 期：3
- 页码：371-373
- 全文大小：133 K
文摘
We tested a mycobacteriophage D29-based method for fluoroquinolone susceptibility assessment in clinical isolates of Mycobacterium tuberculosis. The method was incapable of identifying susceptible strains as such, although a slightly different published protocol successfully identified resistant and susceptible strains. Thus, caution is necessary when choosing an “in-house” D29-based protocol for testing of drug resistance.