Study on the interactional behaviour of transition metal ions with myoglobin: A detailed calorimetric, spectroscopic and light scattering analysis
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- 作者：Amandeep Kaur ; Parampaul K. Banipal ; Tarlok S. Banipal ; tsbanipal@yahoo.com
- 关键词：Myoglobin ; Zinc ion ; Nickel ion ; Manganese ion ; Calorimetry ; Light scattering ; Spectroscopy
- 刊名：Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
- 出版年：2017
- 出版时间：5 March 2017
- 年：2017
- 卷：174
- 期：Complete
- 页码：236-244
- 全文大小：1063 K
- 卷排序：174
文摘
Zn2 + and Ni2 + ions binding with Mb is exothermic whereas Mn2 + ion binding is an endothermic process. Insignificant exposure/burial of the hydrophobic groups occurs in Mb due to binding of Mn2 + and Zn2 + ions. The binding of Zn2 + and Mn2 + ions decreases the size of Mb whereas Ni2 + ion increases it. Zn2 + and Mn2 + ions provide conformational stability but Ni2 + ion provides conformational destability to Mb. M2 + ions do not interact with the heme moiety of Mb.