Hyperlipidemia sink for anesthetic agents
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- 作者：Thomas J. Johnson ; DOa (Professor of Anesthesiology) ; Jahan Porhomayon ; MD ; FCCP ; FCCMa ; jay12p@yahoo.com" class="auth_mail" title="E-mail the corresponding author (Assistant professor of Anesthesiology) ; Nader D. Nader ; MD ; PhDa (Professor of Anesthesiology) ; Enas Eldesouki ; MDa (Assistant professor of Anesthesiology) ; Kelly Smith ; DOb (Doctor of Pharmacy) ; Geoffrey G. Hobika ; MDa (Assistant Professor Anesthesiology)
- 关键词：Hyperlipidemia ; Propofol ; Induction ; Delay ; Anesthesia ; Sink
- 刊名：Journal of Clinical Anesthesia
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：34
- 期：Complete
- 页码：436-438
- 全文大小：229 K
文摘
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Propofol action can be delayed due to severe hyperlipidemia.
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The exact mechanism is unknown but may be due to propofol binding to serum lipoproteins.
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Clinicians must be aware of this interindividual variability in pharmacokinetic of propofol.