Predicting chronic copper and nickel reproductive toxicity to Daphnia pulex-pulicaria from whole-animal metabolic profiles
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- 作者：Nadine S. Taylora ; d ; n.s.taylor@bham.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Jennifer A. Kirwanb ; Craig Johnsona ; Norman D. Yanc ; Mark R. Viantb ; John M. Gunnd ; James C. McGeera
- 关键词：Ecotoxicology ; Environmental risk assessment ; Metal mixtures ; PLS-R ; Metabolomics ; Mass spectrometry
- 刊名：Environmental Pollution
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：212
- 期：Complete
- 页码：325-329
- 全文大小：619 K
文摘
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Very low metal concentrations significantly impair Daphnia pulex-pulicaria reproduction.
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Metabolomics data from chronic metal exposures is predictive of reproductive output.
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Multivariate statistical models can predict chronic impairment from acute metabolomics data.