No relation between sympathetic outflow to muscles and respiratory function in amyotrophic lateral sclerosis
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- 作者：Kazumasa Shindo ; kshindo@yamanashi.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Mai Tsuchiya ; Yuta Ichinose ; Akiko Onohara ; Megumi Fukumoto ; Kishin Koh ; Ryusuke Takaki ; Nobuo Yamashiro ; Fumikazu Kobayashi ; Takamura Nagasaka ; Yoshihisa Takiyama
- 关键词：ALS ; amyotrophic lateral sclerosis ; HR ; heart rate ; MBP ; mean blood pressure ; MSNA ; muscle sympathetic nerve activity
- 刊名：Journal of the Neurological Sciences
- 出版年：2015
- 出版时间：15 November 2015
- 年：2015
- 卷：358
- 期：1-2
- 页码：66-71
- 全文大小：812 K
文摘
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The relation between respiratory function and MSNA was analyzed in ALS.
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There were no significant correlations between MSNA and PaO2, PaCO2, or %VC.
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Analysis of chronological changes in patients examined twice was performed.
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HR, BP, MSNA, and age-adjusted MSNA exhibited no significant changes.
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Abnormality of the autonomic nervous system is a primary feature of ALS.