- 作者：Hiroaki Kajiyama ; Kiyosumi Shibata ; Shiro Suzuki ; Kazuhiko Ino ; Eiko Yamamoto ; Kimio Mizuno ; Katsumi Sakakibara ; Katsuji Matsuzawa ; Akihiro Takeda ; Yoshito Kinoshita ; Michiyasu Kawai ; Tetsuro Nagasaka
- 关键词：Clear-cell carcinoma of the ovary (CCC) ; Fertility-sparing surgery ; Pregnancy ; Clinical outcome
- 刊名：Gynecologic Oncology
- 出版年：2008
- 出版时间：December 2008
- 年：2008
- 卷：111
- 期：3
- 页码：523-526
- 全文大小：138 K
BackgroundIn epithelial ovarian cancer (EOC), fertility-sparing surgery (FSS) has mainly been chosen for stage IA disease. The purpose of this study was to clarify the clinical outcome of patients with clear-cell carcinoma of the ovary (CCC) who would usually undergo radical surgery.Cases
After a central pathological review and search of the medical records from multiple institutions between 1988 and 2005, a total of 10 CCC patients treated with FSS were retrospectively evaluated in the current study. The mean age was 35.9 years (range: 32–39 years). The median follow-up time was 35.4 months (range: 21.7–153.2 months). The stage was IA in 4 patients, and IC in 6 patients {IC(b) in 5 patients, and IC(2) in one}. Nine patients received adjuvant chemotherapy. Nine patients were alive and one patient with stage IC(2) died of the disease at a follow-up time of 36.8 months. Five pregnancies were observed in 4 patients.
Conclusions
Although there is no worldwide criterion for FSS in CCC patients at present, it seems that, in selected patients, this surgical approach could be adopted. This should be investigated by additional studies in a larger series.