Cigarette smoke-induced reduction in binding of the salivary translocator protein is not mediated by free radicals
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- 作者：R. Nagler
- 关键词：Oral cancer ; Saliva ; Cigarette smoke ; 18 kDa translocator protein (TSPO) ; Free radicals ; Aldehydes
- 刊名：Biochimie
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：121
- 期：Complete
- 页码：1-4
- 全文大小：296 K
文摘
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- <p id="p0010">Exposure to cigarette smoke (CS) with saliva is the main inducer of oral cancer.p>
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- <p id="p0015">Presence of TSPO in human saliva has been linked to oral cancer.p>
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- <p id="p0020">We investigated the mechanism behind the CS-induced reduction of TSPO binding.p>
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- <p id="p0025">None of the free radicals tested is involved in CS-induced TSPO binding reduction.p>
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- <p id="p0030">CS affects TSPO binding via mechanisms other than free radicals or volatile aldehydes.p>