<p id="p0010">Haploidentical transplantation offers an attractive alternative in the absence of an HLA closely matched donor and is increasingly popular.p>
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<p id="p0015">Haploidentical transplantation is an especially attractive approach in developing countries or those with constrained resources because of overall reduced costs.p>
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<p id="p0020">A variety of immunomodulation techniques is practiced worldwide to overcome the inherent immunological barriers in haploidentical transplantation.p>
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<p id="p0025">Questions persist and are being actively investigated.p>