Circadian Gene Circuitry Predicts Hyperactive Behavior in a Mood Disorder Mouse Model
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- 作者：Hideo Hagihara1 ; 2 ; Tomoyasu Horikawa3 ; Hironori K. Nakamura1 ; 2 ; Juzoh Umemori1 ; 2 ; Hirotaka Shoji1 ; 2 ; Yukiyasu Kamitani3 ; 4 ; Tsuyoshi Miyakawa1 ; 2 ; 5 ; miyakawa@fujita-hu.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：29 March 2016
- 年：2016
- 卷：14
- 期：12
- 页码：2784-2796
- 全文大小：4053 K
文摘
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Gene expressions of αCaMKII (Camk2a) mutant mice, a bipolar disorder model, are analyzed
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Gene expression patterns in the mouse brain retrospectively predict behavioral state
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Expression of many circadian genes correlates with infradian rhythm behavior
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Expression of molecules in the cAMP/CREB pathway also correlates with the behavior