Coaxial electrospun aligned tussah silk fibroin nanostructured fiber scaffolds embedded with hydroxyapatite-tussah silk fibroin nanoparticles for bone tissue engineering
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文摘

A designing scaffold strategy to imitate the mineralized collagen bundles in natural bone was presented.

Aligned nanostructured composite fibers were fabricated by coaxial electrospinning using green water solvent.

Mechanical properties of aligned TSF nanofiber had been significantly improved by embedding with composite nanoparticles.

Composite scaffolds effectively supported proliferation of MG-63 cells and promoted biomineralization.

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