Postoperative antibiotics are not associated with decreased wound complications among patients undergoing appendectomy for complicated appendicitis

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• 作者：Dennis Y. Kim ; M.D.^a ; ^{dekim@dhs.lacounty.gov" class="auth_mail" title="E-mail the corresponding author} ; Nariman Nassiri ; M.D. ; M.P.H.^a ; Darin J. Saltzman ; M.D. ; Ph.D.^b ; Michael P. Ferebee ; B.Sc.^b ; Ian T. Macqueen ; M.D.^b ; Camille Hamilton ; B.A.^a ; Hamid Alipour ; M.D.^a ; Amy H. Kaji ; M.D. ; Ph.D.^c ; Ashkan Moazzez ; M.D. ; E.M.P.H.^a ; David S. Plurad ; M.D.^a ; Christian de Virgilio ; M.D.^a
• 关键词：Appendicitis ; Complicated ; Perforated ; Gangrenous ; Postoperative Antibiotics ; Complications
• 刊名：The American Journal of Surgery
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：210
• 期：6
• 页码：983-989
• 全文大小：168 K

文摘

The objective of this study was to determine the role of postoperative antibiotics in reducing complications in patients undergoing appendectomy for complicated appendicitis.

Methods

We performed a 5-year retrospective cohort study of adult patients who underwent appendectomy for acute appendicitis. Patients with complicated appendicitis (perforated or gangrenous) were analyzed on the basis of whether they received postoperative antibiotics. Main outcome measures were wound complications, length of stay (LOS), and readmission to hospital.

Results

Of 410 patients with complicated appendicitis, postoperative antibiotics were administered to 274 patients (66.8%). On univariate and multivariate analyses, postoperative antibiotics were not associated with decreased wound complications or readmission, but independently predicted an increased LOS (P = .01).

Conclusions

Among patients with complicated appendicitis, postoperative antibiotics were not associated with a decrease in wound complications but did result in an increased hospital LOS.