Structural analysis of Centrolobium tomentosum seed lectin with inflammatory activity
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- 作者：Alysson Chaves Almeidaa ; Vinicius Jose da Silva Osternea ; Mayara Queiroz Santiagoa ; Vanir Reis Pinto-Juniora ; Jose Caetano Silva-Filhob ; Claudia Figueiredo Lossioa ; Francisco Lucas Faustino Nascimentoc ; Ricardo Patricio Honorato Almeidad ; Claudener Souza Teixeirad ; Rodrigo Bainy Leale ; Plinio Delatorreb ; Bruno Anderson Matias Rochad ; Ana Maria Sampaio Assreuyc ; Kyria Santiago Nascimentoa ; Benildo Sousa Cavadaa ; bscavada@ufc.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Lectin ; Centrolobium tomentosum ; Primary structure ; Crystal structure ; Proinflammatory activity ; Molecular docking
- 刊名：Archives of Biochemistry and Biophysics
- 出版年：2016
- 出版时间：15 April 2016
- 年：2016
- 卷：596
- 期：Complete
- 页码：73-83
- 全文大小：4771 K
文摘
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We present the amino acid sequence of Centrolobium tomentosum lectin (CTL).
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This is the first report of a crystal structure from the genus Centrolobium.
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We evaluated the inflammation activity of CTL in rat paw edema model.
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CTL was submitted to molecular docking with different carbohydrates.