Evaluation of three neutral capillary coatings for the determination of analyte-cyclodextrin binding constants by affinity capillary electrophoresis. Application to N,N′-disubstituted piperazine derivatives.
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- 作者：Cé ; cile Danela ; cecile.danel@univ-lille2.fr" class="auth_mail" title="E-mail the corresponding author ; Patricia Melnykb ; patricia.melnyk@univ-lille2.fr" class="auth_mail" title="E-mail the corresponding author ; Nathalie Azarouala ; nathalie.azaroual@univ-lille2.fr" class="auth_mail" title="E-mail the corresponding author ; Paul-Emmanuel Larchanché ; b ; paul-emmanuel.larchanche@univ-lille2.fr" class="auth_mail" title="E-mail the corresponding author ; Jean-Franç ; ois Goossensa ; jean-francois.goossens@univ-lille2.fr" class="auth_mail" title="E-mail the corresponding author ; Claude Vacchera ; claude.vaccher@univ-lille2.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Affinity capillary electrophoresis ; Cyclodextrin ; Neutral coating ; Hydroxypropyl cellulose ; Polyethylene oxide ; Poly(N ; N-dimethylacrylamide)
- 刊名：Journal of Chromatography A
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：1455
- 期：Complete
- 页码：163-171
- 全文大小：996 K
文摘
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Three neutral coatings are evaluated to avoid the analyte and CD adsorption.
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CD adsorption on the HPC and PEO coatings is proved.
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PDMA coating allows to determine polycationic analyte-CD binding constants.
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Complex structure is elucidated through structure-binding constant relationships.