RNA deep sequencing detected 13,461 genes in primary rat ovarian granulosa cells.
RNA deep sequencing showed that FSH regulates 3772 genes ≥2.0-fold.
Sixty % of the genes regulated by FSH are activated or repressed by FOXO1.
Pathway Studio Analysis revealed enrichment of genes repressed by FOXO1 in metabolism, signaling, transport, and development.
Pathway Studio Analysis revealed enrichment of genes activated by FOXO1 in signaling, cytoskeletal functions, and apoptosis.