The TMP LC50-48 h in nauplius was 156 mg/L and LC50-96 h in adult was 200 mg/L.
TMP-exposed Tigriopus japonicus showed developmental delay and reproduction impairment.
TMP induced oxidative stress via the regulation of antioxidant related genes.
TMP induced expression of three Tj-CYP genes (Tj-CYP3024A2, Tj-CYP3024A3 and Tj-CYP3027C2).